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Divakar Kolhe
Divakar Kolhe

Understanding the Procedure—How Drug Eluting Balloon Angioplasty Works

Drug eluting balloon angioplasty is a minimally invasive technique performed under local anesthesia. It begins with inserting a small catheter into the artery, usually through the groin or wrist. The balloon is carefully guided to the narrowed section of the vessel.


Once in position, the balloon is inflated for several seconds. This simultaneously widens the artery and transfers the drug into its inner layers. After drug delivery, the balloon is deflated and removed—leaving no implant behind.


Patients often experience immediate improvement in blood flow. Recovery times are short, and most individuals resume normal activities within a day. Follow-up imaging may be scheduled to ensure that vessels remain open.


The simplicity of the procedure, combined with the powerful therapeutic effects of the drug coating, has made DEBs a preferred option in many treatment plans.


FAQs


1. How long does inflation last?


Divakar Kolhe
Divakar Kolhe

The Role of Genetic Engineering in Advancing Oncolytic Virotherapy

Oncolytic virotherapy has become one of the most innovative branches of cancer treatment, largely due to advances in genetic engineering. Modern bioengineering techniques allow scientists to create viruses that are far safer, more targeted, and more effective than their naturally occurring counterparts. By modifying specific genes, researchers can fine-tune viral behavior so the virus selectively attacks cancer cells while leaving healthy cells unharmed.


One of the major breakthroughs is the ability to delete virulence genes responsible for harming normal tissues. These deletions ensure viruses remain harmless in healthy environments but thrive inside cancer cells. Many tumors lack key antiviral defenses, enabling the engineered virus to replicate efficiently inside them. This selective replication results in tumor cell death through lysis, releasing viral progeny that continue spreading within the tumor.


Genetic engineering also makes it possible to add new functional genes to the viral genome. These “payload genes” can enhance anti-tumor responses—such…


Divakar Kolhe
Divakar Kolhe

“Heparin and Pregnancy: A Trusted Anticoagulant for High-Risk Cases”

While some medications must be avoided during pregnancy, Heparin is often considered safe and effective under medical supervision. Pregnant individuals with conditions such as clotting disorders, previous miscarriages due to thrombosis, or mechanical heart valves may require anticoagulation to ensure both maternal and fetal safety. Because Heparin does not cross the placenta, it does not directly affect the developing baby, making it a preferred choice over other anticoagulants during pregnancy.


The medication is most commonly administered through daily injections and requires ongoing monitoring to ensure the proper dose. Many women use Heparin throughout pregnancy to maintain stable blood flow and reduce the risk of dangerous clot formation. After delivery, Heparin may continue for a short period until the mother’s body stabilizes. Its long-standing safety profile and reliability have made it a cornerstone therapy in managing high-risk pregnancies.


FAQ


1. Is Heparin safe in pregnancy?

Yes, because it does not cross…


Divakar Kolhe
Divakar Kolhe

The Art and Science Behind Compounded Pharmacy Formulations

Compounded pharmacy blends scientific precision with creativity as pharmacists design customized medication formulations. Each compounded product requires an understanding of chemistry, pharmacology, and patient needs. Unlike mass-manufactured medications, compounded drugs are prepared individually using exact calculations to ensure potency and stability. This craftsmanship allows pharmacists to produce creams, capsules, injectables, suspensions, and troches tailored to the patient’s medical situation.


The preparation process involves selecting appropriate excipients, ensuring compatibility, and following sterile or non-sterile compounding guidelines. Quality assurance is essential, with each batch prepared under controlled conditions and subject to verification. This meticulous approach ensures patients receive medications designed precisely for their requirements, contributing to personalized and effective treatment outcomes.


FAQ


1. Do compounded pharmacists need special training?

Yes, compounding requires specialized education and certification.


2. What forms of medication can be compounded?


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